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Synthetic method of pharmaceutical intermediate 2,4,6-Trihroxybenzoic acid


2,4,6-Trihroxybenzoic acid is important pharmaceutical intermediate, 2,4,6-Trihroxybenzoic acid is white powder, flash point 164.481 °C, boiling point 373℃, relative density 1.924 g/cm3. Irritating to eyes, respiratory system and skin, in contact with eyes, please rinse immediately with plenty of water and seek for medical advice, the operator should wear suitable gloove, eyes protector or mask.
Preparation process:

(1) Synthetic reaction

(2) Acidification

(3)Refining of crude product

 
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